San Isidro is a census-designated place (CDP) in Starr County, Texas, United States. It has a population of 240. The city named for the patron saint of farmers. It has a median income of $20.000 per family. San Isidro is served by the San Isidro Independent School District and is home to the San Isidro High School Tigers. A catholic church was erected in the city in 1900 and a post office was built in 1904. The founder is not Santiago Peña but in fact Blas Pena Gonzales - died 1905 and buried in his ranch family plot in San Isidro Tx.
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