San Perlita (Santa Perlita) is a city in Willacy County, Texas, United States. It has a population of 573 according to the last census. The median income of the city is about $22.000. South Texas Independent School District operates magnet schools that serve the community. The city was established in 1923 and the post office was set up in 1929. The railroad arrived a year later and that was the most prosperous time for the city. It lost as much as half of its population during the Great Depression.
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